Daprostat 2mg Tablets (30s)

Product Overview

Daprodustat is an oral medicine used to treat anemia related to chronic kidney disease by stimulating red blood cell production; available for home delivery across Pakistan. This description refers to the active ingredient daprodustat (2 mg tablet).

Key Benefits

Daprodustat helps raise and maintain haemoglobin in people with kidney-related anemia.

- Oral tablet taken once daily — avoids injections.

- Shown to be effective in patients on dialysis and in clinical studies for non-dialysis chronic kidney disease.

- Allows dose adjustment based on haemoglobin response.

Directions for Use

Use exactly as prescribed by a doctor with regular blood tests to guide dose changes.

Adults

Adults take the tablet once daily; the starting dose and adjustments depend on current haemoglobin and prior treatment with erythropoiesis-stimulating agents. Regular monitoring of haemoglobin, blood pressure and iron status is required.

Children (Paediatric)

Use in children is not established. Daprodustat should only be used in paediatric patients under specialist advice and monitoring.

Pregnancy & Breastfeeding

Advice is cautious because safety data in pregnancy and lactation are limited.

Pregnancy

There is insufficient reliable human pregnancy safety data; use only if clearly needed and after discussion with a doctor.

Breastfeeding

It is not known whether daprodustat passes into breast milk; breastfeeding mothers should consult a doctor before use.

Precautions & Interactions

Check with your doctor about medical history and other medicines before starting daprodustat.

Precautions

• Monitor haemoglobin regularly; excessive rise increases clot risk.
• Monitor blood pressure and cardiovascular status.
• Avoid use if known hypersensitivity to the drug.
• Caution with active or recent thromboembolic disease.

Major Drug & Product Interactions

• Strong CYP2C8 inhibitors (for example certain lipid‑lowering drugs) may raise daprodustat levels — monitoring and dose adjustment may be needed.
• Starting or stopping certain antiplatelet or anticoagulant medicines can affect overall cardiovascular risk; inform your doctor.
• Inform prescribers about all medicines so interactions can be checked.

Adverse Effects

Common Side Effects

• Nausea, diarrhoea, or stomach discomfort.
• Headache.
• Raised blood pressure.
• Injection-free formulation can still cause gastrointestinal symptoms.

Serious Side Effects

- Signs of blood clots (sudden chest pain, breathlessness, leg swelling, or sudden numbness/weakness): stop and seek emergency care.

- Severe or rapidly rising blood pressure.

- Allergic reactions (rash, swelling, difficulty breathing).

- Significant liver test changes or other severe reactions — report to your doctor immediately.

Always follow your prescriber’s instructions and attend scheduled blood tests while using daprodustat. If you are unsure, contact your healthcare provider before making changes.