Daplazole 60mg Capsules (30s)

Daplazole contains dexlansoprazole, a proton-pump inhibitor that reduces stomach acid production. It is used for acid-related conditions such as erosive oesophagitis and gastroesophageal reflux disease.

• Manufacturer Name: AGP
• Drug Class: Proton-pump inhibitor
• Dosage Form: Dual Delayed-Release Capsule
• Storage: Store at room temperature, protected from direct light, heat and moisture. Keep out of reach of children.
• Pack Size: Pack of 30 Capsules

Daplazole 60mg Capsules (30s) Available Online in Pakistan

Dwatson offers Daplazole 60mg Capsules (30s) at Rs.1008, with fast, discreet delivery across Pakistan.

• Dexlansoprazole 60 mg

• Healing of all grades of erosive oesophagitis, generally for up to 8 weeks.
• Short-term treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease.
• Maintenance of healed erosive oesophagitis and relief of associated heartburn when prescribed by a healthcare professional.

For Adult

• For healing of erosive oesophagitis: take one 60 mg capsule once daily for up to 8 weeks, as directed by a doctor.
• Swallow the capsule whole; do not chew or crush it.
• It may generally be taken with or without food. Follow the prescribed duration and dose.

For Children

• Use in adolescents aged 12 years and older only under medical supervision.
• The 60 mg strength is generally used for healing erosive oesophagitis; pediatric dosing should be individualized.
• Safety and effectiveness have not been established for children under 12 years, and use is not recommended unless specifically prescribed.

Side Effects

• Common effects may include diarrhea, abdominal pain, nausea, vomiting, flatulence and upper-respiratory-tract symptoms.
• Other possible effects include headache, constipation, dry mouth and indigestion.
• Long-term or high-dose use may be associated with low magnesium, vitamin B12 deficiency, reduced absorption of some nutrients, Clostridioides difficile-associated diarrhea and osteoporosis-related fractures.
• Seek urgent care for allergic reactions, breathing or swallowing difficulty, severe skin rash, persistent watery diarrhea, seizures, severe weakness or irregular heartbeat.

Contraindications

• Do not use in patients with known allergy to dexlansoprazole, other proton-pump inhibitors or any capsule ingredient.
• Do not use with rilpivirine-containing medicines.
• Avoid or seek specialist advice in severe liver impairment.
• Use the lowest effective dose for the shortest appropriate duration, particularly during long-term treatment.
• Seek medical advice for persistent or severe diarrhea, unexplained weight loss, difficulty swallowing, vomiting blood or black stools.

Precautions & Warnings

• Do not combine with rilpivirine-containing products.
• Use caution with medicines whose absorption depends on stomach acidity, including some HIV medicines, antifungals and certain cancer medicines.
• Monitor or seek medical advice when used with warfarin, digoxin, high-dose methotrexate, tacrolimus, mycophenolate mofetil, iron salts or medicines metabolized through CYP2C19 or CYP3A4.
• CYP2C19 or CYP3A4 inducers such as rifampicin and St. John’s wort may reduce its effect; strong inhibitors such as voriconazole may increase exposure.
• Tell the doctor or pharmacist about all prescription medicines, over-the-counter products, supplements and herbal remedies.

• Use during pregnancy only when clearly needed and prescribed after medical assessment.
• Available proton-pump-inhibitor data do not indicate a major overall fetal risk, but direct pregnancy data for dexlansoprazole are limited.
• There is limited direct information on dexlansoprazole during breastfeeding; consult a healthcare professional before use.