Combiviar 40mcg/6mcg Rotacaps (40s)

Description

Combiviar is an inhaled combination medicine containing budesonide and formoterol for maintenance treatment of asthma and chronic obstructive pulmonary disease. Each rotacap is intended for inhalation through a compatible dry-powder inhaler and should not be swallowed.

• Manufacturer Name: Highnoon
• Drug Class: Inhaled corticosteroid and long-acting beta2-adrenergic agonist combination
• Dosage Form: Dry-Powder Inhalation Capsule (Rotacap)
• Storage: Store below 25°C in a dry place, protected from moisture, heat, and direct sunlight. Keep the capsules in the original packaging until use and keep out of reach of children.
• Pack Size: Pack of 40 Capsules

Ingredients

• Budesonide 400 mcg
• Formoterol fumarate equivalent to formoterol 6 mcg

Benefits

• Maintenance treatment of asthma when inhaled corticosteroid and long-acting bronchodilator therapy are appropriate.
• Maintenance treatment of chronic obstructive pulmonary disease with persistent airflow limitation and recurrent symptoms.
• Helps reduce airway inflammation, wheezing, breathlessness, and bronchoconstriction.

Usage & Safety

For Adult

• Use only by oral inhalation with the prescribed compatible rotacap inhaler; do not swallow the capsule.
• A commonly prescribed adult regimen is one rotacap inhaled twice daily, but the exact dose and frequency must be individualized by the prescriber.
• Load the capsule into the inhaler immediately before use, pierce it according to the device instructions, and inhale the powder deeply through the mouth.
• Rinse the mouth with water and spit it out after each dose to reduce the risk of oral thrush and hoarseness.
• This product is not intended to provide immediate relief during a sudden severe asthma attack; use the prescribed rescue inhaler for acute symptoms.

For Children

• Pediatric use should be determined by a physician based on age, diagnosis, symptom severity, and ability to use the inhaler correctly.
• Safety and effectiveness of this specific 400 mcg/6 mcg rotacap strength are not established for young children.
• Children should use the product only under adult supervision and should not swallow the capsule.
• No weight-based dosing recommendation is established; do not adjust the dose according to body weight without medical advice.

Side Effects

• Common effects may include throat irritation, hoarseness, cough, headache, tremor, nervousness, muscle cramps, nausea, and palpitations.
• Oral candidiasis may occur; rinsing and spitting after inhalation can help reduce this risk.
• Formoterol may cause fast heartbeat, blood-pressure changes, or low potassium, particularly with excessive use or in susceptible patients.
• Serious effects may include paradoxical bronchospasm, significant arrhythmia, severe allergic reaction, adrenal suppression, vision changes, or pneumonia.
• Report persistent white patches in the mouth, worsening wheezing, severe weakness, irregular heartbeat, or signs of infection.

Contraindications

• Do not use in patients with known allergy to budesonide, formoterol, lactose or any other component.
• Do not use as the sole treatment for acute bronchospasm or status asthmaticus.
• Use cautiously in patients with heart disease, arrhythmias, hypertension, hyperthyroidism, diabetes, seizure disorders, osteoporosis, glaucoma, cataracts, or untreated respiratory infections.
• Inhaled corticosteroids may increase the risk of oral fungal infections, pneumonia, adrenal suppression, reduced bone mineral density, and growth effects with prolonged or high-dose use.
• Seek urgent medical care for worsening breathing, rapidly increasing rescue-inhaler use, chest pain, severe palpitations, facial swelling, or difficulty breathing immediately after inhalation.

Precautions & Warnings

• Other long-acting beta2 agonists or excessive use of short-acting beta2 agonists may increase cardiovascular and low-potassium effects.
• Beta-blockers, including some eye drops, may reduce the bronchodilator effect and can cause bronchospasm.
• Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, ritonavir, and cobicistat may increase budesonide exposure and corticosteroid-related effects.
• Diuretics, corticosteroids, methylxanthines, and some medicines that prolong the QT interval may increase the risk of low potassium or cardiac effects.
• Monoamine oxidase inhibitors and tricyclic antidepressants may enhance cardiovascular effects; inform the prescriber before use.
• There are no important routine food restrictions, but grapefruit products should be discussed with a healthcare professional when strong CYP3A4-inhibiting medicines are being used.

Pregnancy

• Use during pregnancy only when clearly needed and under medical supervision; uncontrolled asthma can also pose risks to the mother and fetus.
• Available evidence for inhaled budesonide is generally reassuring, but the combination should be continued, started, or changed only on professional advice.
• Tell the prescriber if pregnancy is planned or confirmed; use the lowest effective dose that maintains control.
• It is not known whether clinically significant amounts pass into breast milk. Consult a healthcare professional before breastfeeding use.

Combiviar 400mcg/6mcg Rotacaps (40s) Available Online in Pakistan

Dwatson offers Combiviar 400mcg/6mcg Rotacaps (40s) at Rs. 728.8, with fast, discreet delivery across Pakistan.