Actif 40mg Capsules (14s)

Actif 40mg Capsules contain esomeprazole, a proton pump inhibitor that reduces stomach acid production. It is used for acid-related conditions such as gastroesophageal reflux disease, erosive esophagitis, and peptic ulcer disease.

• Manufacturer Name: Webros
• Drug Class: Proton pump inhibitor
• Dosage Form: Capsule
• Storage: Store at room temperature in a dry place, protected from heat, moisture, and direct light. Keep in the original packaging and out of reach of children.
• Pack Size: Pack of 14 Capsules

Actif 40mg Capsules (14s) Available Online in Pakistan

Dwatson offers Actif 40mg Capsules (14s) at Rs.170, with fast, discreet delivery across Pakistan.

• Esomeprazole 40 mg

• Relief and treatment of gastroesophageal reflux disease and acid reflux symptoms
• Healing and maintenance of erosive esophagitis
• Treatment of stomach and duodenal ulcers
• Part of combination therapy for Helicobacter pylori infection
• Prevention or treatment of ulcers associated with nonsteroidal anti-inflammatory medicines when prescribed
• Management of conditions involving excessive stomach acid production, such as Zollinger–Ellison syndrome

For Adult

• Common adult dose for acid reflux or gastroesophageal reflux disease: 20 mg to 40 mg once daily, usually taken before food.
• For erosive esophagitis, 40 mg once daily may be used for a limited treatment period as prescribed.
• For Helicobacter pylori eradication, esomeprazole is used with prescribed antibiotics; the regimen and duration must follow the physician’s instructions.
• Swallow the capsule whole with water. Do not crush or chew it unless the product instructions specifically allow an alternative administration method.
• Use the lowest effective dose for the shortest appropriate duration under medical supervision.

For Children

• Use in children only on the advice of a healthcare professional.
• Children aged 1 to 11 years generally require lower, weight- or condition-based doses and may not be suitable for this 40 mg strength.
• Adolescents aged 12 years and older may receive adult-type dosing for selected indications when prescribed.
• Do not use this 40 mg capsule in children below 1 year unless specifically directed by a specialist.

Side Effects

• Common effects may include headache, abdominal pain, diarrhea, constipation, nausea, vomiting, and flatulence.
• Other possible effects include dry mouth, dizziness, and skin reactions.
• Seek urgent medical attention for facial or throat swelling, breathing difficulty, severe rash, blistering or peeling skin, persistent severe diarrhea, jaundice, reduced urination, or symptoms of severe electrolyte imbalance.
• Long-term use may rarely be associated with low magnesium, vitamin B12 deficiency, bone fractures, or kidney problems.

Contraindications

• Do not use in people with a known allergy to esomeprazole, other proton pump inhibitors, or any capsule ingredient.
• Do not combine with medicines containing rilpivirine unless specifically directed by a physician.
• Seek medical evaluation for unexplained weight loss, difficulty or pain when swallowing, persistent vomiting, vomiting blood, black stools, severe abdominal pain, or suspected gastrointestinal bleeding before starting treatment.
• Use cautiously in people with severe liver disease, osteoporosis, vitamin B12 deficiency, low magnesium, or a history of fundic gland polyps.
• Long-term or high-dose use may increase the risk of low magnesium, vitamin B12 deficiency, bone fractures, intestinal infections, and kidney inflammation.

Precautions & Warnings

• Do not use with rilpivirine-containing products unless specifically instructed by a doctor.
• Esomeprazole may reduce the effectiveness of clopidogrel; discuss alternative acid-reducing treatment with a healthcare professional.
• Use caution with high-dose methotrexate because proton pump inhibitors may increase methotrexate levels and toxicity risk.
• It may affect medicines whose absorption depends on stomach acidity, including some antifungal medicines, iron products, and mycophenolate.
• Tell the doctor about warfarin, digoxin, tacrolimus, phenytoin, diazepam, rifampicin, HIV medicines, and St. John’s wort before use.
• Food is not usually a major interaction, but the capsule is generally taken before meals. Avoid self-medicating with additional acid-reducing products without advice.

• Use during pregnancy only when recommended by a healthcare professional after considering the benefits and potential risks.
• Available evidence for proton pump inhibitors has not shown a major increase in birth-defect risk, but direct information for esomeprazole remains limited.
• Small amounts may pass into breast milk; consult a healthcare professional before use while breastfeeding.
• Report any unusual symptoms in a breastfed infant to a healthcare professional.