Actif 20mg Capsules (14s)

Actif 20mg is an oral acid-reducing medicine containing esomeprazole. It is used to relieve excess stomach acid and manage acid-related gastrointestinal conditions such as reflux and heartburn.

• Manufacturer Name: Webros
• Drug Class: Proton-pump inhibitor
• Dosage Form: Capsule
• Storage: Store at room temperature in a dry place, protected from heat, moisture, and direct sunlight. Keep out of reach of children.
• Pack Size: Pack of 14 Capsules

Actif 20mg Capsules (14s) Available Online in Pakistan

Dwatson offers Actif 20mg Capsules (14s) at Rs.140, with fast, discreet delivery across Pakistan.

• Esomeprazole 20 mg

• Relief and treatment of gastroesophageal reflux disease and frequent heartburn
• Healing and maintenance treatment of erosive esophagitis
• Treatment of acid-related dyspepsia and other acid-peptic symptoms
• Part of combination therapy for Helicobacter pylori eradication when prescribed
• Prevention or treatment of gastric and duodenal ulcers associated with nonsteroidal anti-inflammatory medicines when prescribed
• Management of pathological gastric acid hypersecretion under specialist supervision

For Adult

• For common reflux symptoms, the usual adult dose is 20 mg once daily, generally taken before food.
• For erosive esophagitis or other diagnosed acid-related conditions, the usual dose may be 20 to 40 mg once daily as directed by a healthcare professional.
• Swallow the capsule whole with water; do not crush or chew it.
• Take at approximately the same time each day and use only for the duration recommended by the prescriber.

For Children

• Use in children only on the advice of a pediatrician or other qualified healthcare professional.
• In studied children aged 1 to 11 years, doses have varied from 5 to 20 mg once daily according to age, body weight, and diagnosis.
• Children weighing 20 kg or more may receive up to 20 mg once daily for selected indications under medical supervision.
• This 20 mg capsule may not be appropriate for young children who cannot swallow capsules; an age-appropriate formulation may be required.
• Do not self-treat infants or children with this product.

Side Effects

• Common effects may include headache, abdominal pain, diarrhea, constipation, nausea, vomiting, flatulence, or dry mouth.
• Seek urgent medical help for facial or throat swelling, breathing difficulty, severe rash, blistering or peeling skin, or other signs of a serious allergic reaction.
• Contact a healthcare professional for persistent severe diarrhea, severe or persistent abdominal pain, yellowing of the skin or eyes, dark urine, reduced urine, or unusual tiredness.
• Prolonged use may rarely contribute to low magnesium, vitamin B12 deficiency, bone fractures, kidney inflammation, or infection-related diarrhea.

Contraindications

• Do not use in anyone with a known allergy to esomeprazole, omeprazole, other substituted benzimidazoles, or any capsule ingredient.
• Avoid use with rilpivirine-containing medicines unless specifically approved by a specialist.
• Seek medical assessment before use if there is unexplained weight loss, difficulty or pain when swallowing, persistent vomiting, vomiting blood, black stools, severe abdominal pain, or suspected gastrointestinal bleeding.
• Use cautiously in people with severe liver disease, a history of low magnesium, vitamin B12 deficiency, osteoporosis, or previous serious reactions to acid-suppressing medicines.
• Long-term or repeated use should be medically reviewed because it may be associated with nutrient deficiencies, bone fractures, intestinal infections, or kidney inflammation.

Precautions & Warnings

• Tell the prescriber about all medicines, supplements, and herbal products before use.
• Esomeprazole may reduce the effectiveness of clopidogrel; the combination should generally be avoided unless specifically directed by a healthcare professional.
• It may interact with medicines whose absorption depends on stomach acidity, including some antifungal medicines and certain antiviral medicines.
• Important interactions may occur with warfarin, diazepam, phenytoin, methotrexate at high doses, tacrolimus, digoxin, rifampicin, and some HIV medicines.
• Antacids may sometimes be used with esomeprazole, but regular combined use should be discussed with a pharmacist or doctor.
• Food does not usually cause a dangerous interaction, but taking the capsule before a meal may provide more consistent acid suppression.

• Use during pregnancy only when recommended by a healthcare professional after considering the expected benefits and potential risks.
• Available evidence has not established a clear major risk, but direct pregnancy and breastfeeding data for esomeprazole remain limited.
• Small amounts may pass into breast milk; consult a healthcare professional before breastfeeding while using this medicine.
• Do not start, stop, or continue regular treatment during pregnancy or breastfeeding without medical advice.